UV damage regulates alternative polyadenylation of the RPB2 gene in yeast
نویسندگان
چکیده
منابع مشابه
UV damage regulates alternative polyadenylation of the RPB2 gene in yeast
Alternative polyadenylation (APA) is conserved in all eukaryotic cells. Selective use of polyadenylation sites appears to be a highly regulated process and contributes to human pathogenesis. In this article we report that the yeast RPB2 gene is alternatively polyadenylated, producing two mRNAs with different lengths of 3'UTR. In normally growing wild-type cells, polyadenylation preferentially u...
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A large number of human genes have been found to contain more than one polyadenylation site (poly(A) site). These lead to multiple messenger ribonucleic acid (mRNA) transcripts, although some of them do not yield protein products. Like alternative initiation and alternative splicing, alternative polyadenylation (APA) contributes to the complexity of the overall pool of mRNA transcripts in human...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2013
ISSN: 1362-4962,0305-1048
DOI: 10.1093/nar/gkt020